ESS now invites researchers to apply for support in deuterium labelling and protein crystallisation. The call welcomes users from other neutron facilities and potential future ESS users.
A prerequisite for a successful neutron experiment is obtaining the best sample, characterising and conditioning it properly before and during the experiment.
ESS has several user laboratories where samples can be prepared handled, characterised and stored. Located near the instruments, these laboratories will also allow for the possibility of manipulating the conditions that the sample is in during the neutron investigation.
One of the techniques used to prepare samples for neutron scattering experiments is deuteration or deuterium labelling – a process in which the hydrogen atoms in a molecule are replaced with the heavier isotope of hydrogen called deuterium, which acts as a contrast agent for neutrons. Deuteration is a powerful labelling technique that can give more information about the structure and function of even very complex samples, for example food dispersions, proteins and multi-component drug formulations.
At ESS, deuteration support is provided by the Deuteration Group, which is now issuing a call for proposals of users of other neutron facilities in collaboration with the NMX instrument team for protein crystallisation support.
Looking ahead to first science to be carried out at ESS, the team also accepts proposals for potential experiments on the first ESS instruments that may be submitted in collaboration with ESS instrument scientists.
Researchers interested in participating in this call should reach out to the Deuteration group before applying via the Proposal system to discuss their project idea and seek advice on its feasibility and timescale. More information about the current capabilities can be found in our product catalogue. Support is granted on the basis of technical and scientific review.